Wednesday, December 31, 2014

Christmas Eve Oilahuasca Trial

I tried Oilahuasca on Christmas Eve. It was a mixture of these Herbs, and it tasted bitter, so I just put it in some Milk. Then I ate a Piperine tablet before drinking the Milk and then took 1 Capsule of Kudzu and 2 Capsules of Basil leaf.

Even though I studied the effects I had the feeling that it wasn't going to work for some reason, but around 20 Minutes I started to feel something, then around 45 minutes I definitely noticed the effects. It felt a lot like the first 45 minutes of Mushrooms, when it starts to make you feel different but nothing wiggles yet. It felt really good, but it was just like a cup of coffee that made me feel awesome, it wasn't anything too awesome. But I am going to try it with a larger amount soon, and then I will let everyone know what happens.

http://finshaggy.blogspot.com/2014/12/how-oilahuasca-works.html

Random People Talking About Drug Metabolism

Tuesday, December 30, 2014

How Oilahuasca Works


CYP Enzymes (Drug Metabolism, etc)
Induction and Inhibition (Anti-Oxidants, etc)


Cinnamon Bark- CYP2A6 & CYP2E1 Inhibitor (It will deplete your liver's Glutithione) Taken 1 Hour before Allybenzene,

Clove Leaf- CYP2C9, CYP3A4, CYP1A1 & CYP1B1 Inhibitor 

German Chamomile- CYP1A2 Inhibitor (Caffeine may also do this)



Also

GoldenSseal & Echinacea purpurea very effectively do the same thing. And people have reported using Vitamin B9 or Almond extract or Star Anise Extract and Tangerine Peels or Extract.

The 4 Oils listed are "AllylBenzenes", here is a larger list, but I am not sure if anyone has ever tried to Oilahuasca these yet, and I do not know if it is safe, so I am not suggesting anyone try these, they are just here for the sake of discussing them so people in the future can be safe.



Anethole, Apiol, Asarone, Carpacin, Chavibetol, Chavicol, Dillapiole, Eugenol, Isoeugenol, Isosafrole, Methyl Eugenol, Methyl Isoeugenol,

Here are the things that you need to make sure the Oil works.



Star Anise Extract or B9 for CYP2C9 Induction



Most important things:

CYP2C9 Induction

Alcohol Dehydrogenase Induction

Aldehyde Dehydrogenase Inhibition

Piperidine and or Dimethylamine Supplementation

Methyl from foods

Exercise or compounds that produce effects like exercise



Less important, but still factors:

SSAO Inhibition (Caffeine, Phenethylamine, Phenelalamine, Tryptamine)

MAO-A Induction

MAO-B Induction

NDMA Antagonism

Prolactin Inhibition


Hungarian Parsley Seed is a better source of Myristicin, just found that out. And the effects of it when activated properly are said to be like Mescaline and MDMA together. The P450 Enzymes CYP1A2 & CYP3A4 are what break this down and need to be inhibited. CYP2D6 could also play a big role.

Elmicin is something you either needs Chromotography type knowledge to get, or you have to buy it in small quantities. When activated properly it is like Mescaline, when activated wrong it is like Melatonin (sleepy). CYP1A1, CYP1B1, CYP1A2, CYP2A6, CYP2C9, CYP2A6, CYP2C9 & CYP2E1 are what are needed to be inhibited to activate this. CYP2D6 could also play an important role.

Safrole is like MDMA when activated properly and like Melatonin when not. CYP2A6, CYP2C9, and CYP2E1 are most important for this. CYP2D6 could also be important.

Methyl Chavicol when activated properly is like a light speedy LSD, when activated wrong it is said to be almost like Marijuana. CYP1A2 and CYP2A6 inhibit it, and CYP2D6 could also be important.

If the CYP2D6 Enzyme is inhibited with all the others, these are possibly visually hallucinogenic Oilahuascas. And the Methyl Chavicol doesn't build a tolerance (the others do) it actually gets stronger for you every time you use it, or you can use less. 


Dill seed extract also is said to be able to be used. As one of the main things, like in place of the Chavicol.

And apparently you can turn the main ingredients into 3 different forms, depending what you take:
Dimethylamine, Piperidine and the Pyrrolidine derivatives
Piperidine is said to be the strongest and is made by having Pepper or a Pepper replacement in your system.

And Apparently Elami oil can be activated by Valerian Root of Chinese origin, Coffee, Almond Extract & Glycerin (the stuff E-Cig liquid is made of), and nothing else. And it is like Mescaline. Someone told that guy that he didn't even need the Valerian root, and if he had added Vanilla or Cumin oil to his coffee, it could have been even stronger. So basically if someone were to drink a Nutmeg, Vanilla, Almond Coffee... They could trip and not even expect it. 


Valerian Root, B9, Anise seed are all interchangeable or to be used together
or replaced with:
DHEA (dehydroepiandrosterone)
Eugenol (inhibits/induces CYP2C9)
Ginkgo biloba (inhibits/induces CYP2C9)
Licorice (inhibits/induces CYP2C9)
Milk Thistle
Resveratrol (inhibits CYP2C9)
Saint John’s Wort (inhibits/induces CYP2C9)
Turmeric (inhibits/induces CYP2C9)

Pepper tea, with the solids taken out, seems to be the best thing for creating the base base.

L-Lysine is said to really help the pepper.

Vanilla and Cinnamon seem to be interchangable. They are both Aldehydes. 

German Chamomile does the best at blocking CYP1A2, but you can use Cayenne Peppers or Tangeretin. 

CYP2A6 can be inhibited by:
Almond Extract, Anise oil, Benzaldehyde, Cinnamaldehyde, Lemon oil, Lime oil, Orange oil, Limonene, Tangerine oil, Lemongrass oil, Nicotine

CYP2D6 Inhibition could mean the difference between Psychedelic effects and no effects. Here are the things that inhibit it:
CBD (Cannabidiol from Cannabis), Echinacea Purpurea, Pomegranate, Pummelo, Calamus oil, Kava, Black Cohosh

CYP3A4 is important to inhibit, which can be done with:
Catechin, Clove oil, Dill seed oil, Ginger, Goldenseal, Pomegranate, Cinnamon & Kava.

Kudzu seems to help protect it after it is formed. This can be replaced by Gallic Acid, Soy Isoflavones, Glycerin, Caffeine or Benzaldehydge.

And if anyone were to try these things with Mescaline or MDMA or DMT, they would probably get some awesome effects. I am not sure if anyone has tried it yet, but there may be other versions of Ayahuasca to make, where you take DMT orally and have it made into something else by inhibiting certain enzymes.

Cayenne Peppers promote Endophines and Adrenaline, so they also put things in the body that are helpful. 


From what I read earlier, any NMDA antagonist would be beneficial, but not crucial in the mix. This makes sense to me, because NMDA antagonists are things like, Ecstasy or Cough Medicine (Delsym) or MXE. So it would make sense that having something that has these effects would kind of kick the whole thing into a full blown experience.

So, Dextromotphan, that is what is in Cough Syrup and it is legal to buy, posses, etc. It is not any kind of drug. MXE is legal to buy and posses, but you are not allowed to take it unless you are a member of the Church of NeuroScience.

There are also plants that have these effects:
Uncaria Rhynchophyllia
Psychotria Colorata
Huperzia Serrata

Then there is the addition option of Prolactin Inhibition, which can be done with: 
Zinc, Ginko Vitamin E, B6, Almonds or Almond Extract & Magnesium
And possibly by anything that releases Dopamine or acts like it. So L-DOPA, THC, and a few other things maybe. 

Entheogens

Coffee & Cuban Coffee, in Cuba they boil their coffee down REALLY small amount, so it's a lot stronger. Like if you made a pot of coffee with a coffee machine, then put it in a petal pot on the stove and boiled the pot down to one shot glass.

Guarana, Contains Caffeine and Theobromine. So has the effects of Coffee and Chocolate.

Guyusa, Kinda of like Tea, but it is used in place of Coffee in some places. And is stronger than Tea.

Yerba Mate, Kinda of like Tea, but it is used in place of Coffee in some places. And is stronger than Tea.

Oilahuasca: Oilahuasca is using simple things like Cinnamon/Clove Tea to turn off your P450 Enzymes, then taking something like Basil Extract, to achieve effects like ecstasy. It is similar to how Ayahuasca works.

Enchymoma: A word from the 1800s, it means "An Elixir Made in the Stomache"

Hotentot Tea: A Dream Brew including Imphepho flowers and a few other things, meant to promote dreaming.

Soma: An Ancient Vedic Brew, some Historians believe it is Opium Poppy, some Historians believe it is Amanita Muscaria, some Historians believe it is a brew Similar to Ayahuasca.

Ambrosia: An ancient Greek brew, possibly containing Opium, but definitely containing some kind of Psychoactive plant.

White Lotus Wine: The Ancient Egyptians used to let their Wine soak up the stuff inside Lotus before drinking it, so that they had a Lotus Tea/Wine. White lotus contains a compound that attaches to dopamine receptors.

Kratom: Has been made into tea by Buddhists for hundreds if not thousands of years. Contains Opiates that are not illegal, because they are not the same as the Opiates in Opium. And they may not show up on drug tests, I would double check though.

Lemon Grass: Contains Myrcene which can also be found in Hops/Beer. Has a slight Opiod Analgesic effect.

Black Cohosh: Attaches to 5HT serotonin receptors, can be made into a Tea or Capsule.

Mucuna Seed/Velvet Bean: Contains L-DOPA and Tryptamines, people use it as a Mood Enhancer.

Catnip: Can be made into a tea and drank by humans for light sedative effect, about 80% of cats are effected by it.

Valerian Root: Can effect cats similar to Catnip. Causes sedative effects in humans.

Silver Vine: Can effect cats similar to Catnip. Probably has effects for humans.

Bog Bean Leaves: Can effect cats similar to Catnip, used by humans in place of coffee.

Dittany of Crete: A Cooking Spice grown in Europe, this plant does not drop seeds and can only be cultivated by growing a clone, and it has been passed down this way for a LONG time. It has some sedative effects from what I have read, but I have not tried it.

Voaconga Africana: Contains things similar to Ibogaine and could be used for drug treatment.

Inebriating Mint: Used around Turkey, made like Tea, has a sedative effect.

Indian Warrior: A Natural Sedative/Tranquilizer

Mulungu: Said to be "Nature's Valium" by some people.

Wild Dagga: Contains Leourine, similar to Cannabis but not the same. Can be smoked or made into a tea.

Clip Dagga: Just like Wild Dagga

Motherwort/Siberian Motherwort: Contains the same thing as Wild Dagg and Clip Dagga.

Virola Elongota: Used by people in the Amazon as an entheogen and arrow poison.

Desfontainia: Known as "Chilean Holly", used as a Hallucinogen by native people.

Typha Capensis: Root Mass used as Entheogen

Maconha Brava: Used as an Entheogen in some places.

Black Horehound: Contains Diterpenes and is said to have some entheogen effects.

Stone Root: Has effects on the central nervous system and other parts of the body.

Horny Goat Weed: Used as a Sexual Stimulant for Men

Yohimbe: Used as a Sexual Stimulant for Men and Women

Belladonna Eye Drops: Used to make your eyes Dilated

Passion Flower: MAOI/Antidepressant

Kanna: SSRI/Antidepressant

Aconite aka Monks Hood aka Wolf's Bane. It has been used to kill wolves and was said to turn people in to werewolves. It is poison and can kill someone who eats to much, some people smoke it though.

Acacia is known as "Waddle" in Australia and has species all over the world, the bark contains DMT, 5-MeO-DMT and other Tryptamines.

Acorus Calamus aka Sweet Flag. Can cause hallucinations. It is used in medicine and food.

Amanita Muscaria aka Fly Agaric. Hallucinogenic and possibly Narcotic. You have probably seen them with toads on them, or gnomes under them, or in Alice in Wonderland.

Some species of Ants have been used to achieve ritual hallucinations. Some ants contain hallucinogens you can use by swallowing them.

Ayahuasca is a mixture of 2 things. Any plant containing MAOIs mixed with any plant containing DMT, then drank together.

Belladona seeds are poisonous and have been used to achieve hallucinations for a long time. They say that the reason "witches fly on broom sticks" is because they would use broom sticks to put the Belladona seed in a... weird place. Then they would "Fly".

Betel leaf is chewed by about 1/10th of the world's population as a mild stimulant similar to cigarettes.

Brugmansia contains Scopolamine which can cause vivid hallucinations via making you extremely delirious. It is not a hallucinogen, it is a delliriant and a poison that can kill you.

caesalpinia sepiaria is said to cause hallucinations.

Camellia Sinensis aka Tea Leaves, contains both Caffeine and L-Theanine, which together work differently than either of them would alone.

Cannabis aka Marijuana aka Pot also Hash contains THC and other Cannabinoids.

Chocolate contains Theobromine.

Cantharides aka Spanish Fly. An Aphrodisiac made from the wings of a beetle. Supposedly Sudanese people grind up dung beetles and drink them with water, no known reason for this yet though.

Coca plants contain cocaine and other things. It used to be the main ingredient of Coca-Cola.

Coffee contains Caffeine.

Datura is just like Brugmansia.

Duboisia Hopwoodii aka Pituri grows in Australia and has nicotine and a stronger (more poisonous) relative of nicotine in it.

Ephedra aka Mormon Tea contains Ephedrine, a stimulant which has been used to treat asthma.

Fugu aka Puffer fish. It's liver contains a nuerotoxin that kills most people, some people survive with no vital signs, then wake back up after 3 days. It is a delicacy in Japan because you have to trust the chef to not kill you, even on accident.

Guarana contains both Theobromine and Caffeine.

Heimia Salicifolia aka "Sun Opener" has the ability to turn your vision yellow when you drink it in a tea.

Henbane is poisonous and some people smoke it.

Iboga contains Ibogaine which has in recent times been used to cure Heroine and other opiate addictions. It could also be useful for cigarette smokers and methamphetamine users.

Inebriating Mint is used as a sedative and light hallucinogen in Turkey and a few other places.

Kava Kava has the same descriptive qualities as marijuana (Sedative/Euphoriant), but it is not the same when you take it, they are different. Mixing them together gives them Synergy though.Kava will make your moth numb and does not taste awesome.

Kratom is a sedative or a stimulant depending how much you take, and people chew it or make it into a tea.

lycopodium complanatum has been used by natives as a stimulant.

lycopodium selago causes a "mild narcotic hypnosis" at low doses and coma at high doses.

Mandrake root is poisonous and has historically been used in tons of potions and stuff. It was the plant that had a crying baby as a root in Harry Potter. The roots actually do look like people sometimes and historically they have been involved in all kinds of crazy stuff.

Morning Glory Seeds contain LSA which is a cousin of LSD.

Myelobia Smerintha Moths are said to be able to give you dreams when eaten, and the Aztecs claimed a moth as their underworld God, so someone should see what is in those ones.

the Nightmare fish is known to cause terrible nightmares. It could be kyphosus vaigiensis or kyphosus fuseus.

Osteophloeum Platyspermum is used in Ecuador for it's hallucinogenic properties.

Peyote is known to contain Mescaline.

Psilosybe mushrooms (usually Psilosybe Cubensis) are known as "Magic Mushrooms" commonly.

Puffballs are the mushrooms genuses: Lycoperdon, Bovista and Calvatia and have been known to cause Auditory Hallucinations.

Qat aka Khat is eaten in the middle east, it is used commonly like coffee, but is more like Amphetamine.

San Pedro is similar to Peyote.

Scirpus has traditionally been used as a Hallucinogen in Mexico, but it's effects have not been studied.

Scotch Broom supposedly has hallucinogenic seeds, and leaves that when smoked, make colors seem more vibrant.

Syrian Rue contains MAOIs which shut off parts of your immune system, allowing certain plants to take stronger effect (ex: used in Ayahuasca to make DMT orally effective) but it will also make Chocolate, Alcohol and Cheese poisonous during the duration of its effect on you because you can not break them down properly. This is called the "Cheese Syndrome" or "Cheese Effect"

Tree Tobacco is much like Tobacco but contains nicotine and other things, and it grows in South America.

Wild Lettuce (all lettuce actually, but this one has the most) contains opiates, not the same at the opiates in opium, but they hit the same receptors in the brain. It used to be called "Poor man's opium", and it probably grows in your yard.

Virola is known to contain DMT and other things.

Yohimbe bark is used as an Aphrodisiac and Stimulant for both men and women.

Yopo contains 5-HO-DMT which is mixed with Edible Lime and blown into people's noses in south America.

Uziza: Contains Caryophyllene, which is also in Cannabis and works similar to Cannabinoids.

Syrian Oregano & Thyme: Both of these contain Thymol, which is related to Propofol, which is the stuff that Michael Jackson was using to sleep. Thymol does not act like Propofol only because it is broken down in the stomach and liver.

Betel Leaf and Nut: Contains Chavicol, the leaves and nut are chewed like tobacco all over the world, and drops of extract can be added to a cigarette or joint for a stimulant effect.

Dragon's Head (Dracocephelums): Sedative Effect

Wool Grass: Root mass is used as an Entheogen

Sun Opener: Used as part of a Mixture in Mexico by Natives. It has effects of its own, but they are hard to pin point. Maybe a skeletal muscle relaxant, it has a weird hangover.

Coleus: Used by the same tribe that invented Salvia, it is a Sedative but has not been studied much.

Hops: Contain Myrcene, which works as a light Opiod Analgesic.

Indian Bay Leaves: Contains Caryophyllene

Uncaria Rhynchophylla: Has effects on the NMDA receptor.

Ylang Ylang: Contains Caryophyllene and other Terpenes.

Tecoma Stans: Works in some cats like Catnip. Could have effects in humans.

Tartarian Honey Suckle Bark: Works like Catnip in some cats. Could have effects in humans.

Cigarette Tobacco/Nicotiana Tobaccum: Used for dreaming by Native Americans, not used to Relax or Stimulate.

Jasmine Tobacco: A Species of Tobacco whose flowers smell like Jasmine

Bitter Calea: Used to promote dreaming.

Graviola: 5HT1a Agonist

Senegalia greggii: Native to Texas to California and in Sonora Mexico, the extract has stimulant effects

Red Clover
Ugni Molinae
Casearia Sylvestris
Pachyptera Hymenaea
Prickly Poppy
Adrenorphin (Cow Brain)
Deltorphin (Waxy Leaf Frog)
Dermorphin (Waxy Leaf Frog)
Chaste Tree
Black Kohosh
Laurelia Novae-Zelandiae
Salvia Leriifolia
Salvia Divinorum (Illegal in some places, also very active on other receptors)
Tabernaemontana Pachysiphon
Irvingia Gabonesis
Myrrh
Dalea Purpurea
Nigella Sativa Seed
Sophora Subprostata
Picralima Nitida
Chocolate (Reports say that Chocolate makes other Opiods stronger)
Yellow Horned Poppy
Crydalis Yanhusuo
Spinorphin (Cow Spine)
D-Phenylalanine (Enkephalinas Inhibitor)
Oriental Poppy
Marijuana (CBD is an Opiod)

Dream Herbs

I was researching Hottentot tea, and Hottentot tea. This is mainly Imphepho (an Herb), but is traditionally also used with various other Herbs and if I remember correctly Kanna was one of the things that was used.

I also knew about Silene Capensis being used by the Xhosa tribe, but today while I was looking it up again I found "Ubulawu". This is basically a Ayahuasca/Oilahuasca meant for dreaming. I never got to try Silene Capensis, because it has a special growing cycle and doesn't match up with Marijuana (as I found out), so I only have seeds. But I just ordered some other stuff, and I should have them after Christmas.

Here is what I ordered for an Ubulawu mix:

1. Silene Capensis root (People have gotten results from this alone)
2. Synaptolepis kirkii (Has some pretty interesting Neuroprotective effects and is said to induce Visions)
3. Rhus pauciflorus (Commonly used as an admixture)
4.Acacia xanthophloea (Used for fever and other things)

Then I already had these things (for Hottentot tea) and I will try them all together:

1. Imphepho (Said to Induce Visions, and Contains Diterpenes)
2. Kanna (SSRI)

Then I also have Coleus, which was used by the tribe that used Salvia, but Coleus was used specifically for Dreaming.

Tons of people have taken some of these alone and had really good effects, but tribes in South Africa are known to take all of them together. And if you look in to the history of Python cave and Imphepho, you will see that people have been using these herbs since the first human behavior was developed (Python cave and other Caves in South Africa like Pinnacle Point are places where humans first did some of the things we consider to be "Human Nature".).